Rhodonite was once used as ore of manganese in India. Today its only uses are as lapidary materials and as mineral specimens. High-quality crystals of rhodonite can sell for very high prices. Good massive pink- to red-colored material is used as an ornamental stone or gem rough. It is typically used to make cabochons, beads, small sculptures, tumbled stones, and other lapidary projects.

Rare, well-formed, transparent crystals are highly sought after by mineral collectors. Damaged crystals of good quality are sometimes cut into faceted stones. Most of these are acquired by collectors because their cleavage and low hardness make them too fragile for use in jewelry.